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ChemicalBook CAS DataBase List 4-(4-HYDROXY-PIPERIDIN-1-YL)-BENZONITRILE

4-(4-HYDROXY-PIPERIDIN-1-YL)-BENZONITRILE synthesis

2synthesis methods
-

Yield:79421-43-5 94%

Reaction Conditions:

with potassium carbonate in dimethyl sulfoxide at 120; for 6.5 h;

References:

Huang, Tien L.;Zhang, Qian;White, Angele T.;Queener, Sherry F.;Bartlett, Marilyn S.;Smith, James W.;Donkor, Isaac O. [Bioorganic and Medicinal Chemistry Letters,1996,vol. 6,# 17,p. 2087 - 2090] Donkor, Isaac O.;Huang, Tien L.;Tao, Bin;Rattendi, Donna;Lane, Schennella;Vargas, Marc;Goldberg, Burt;Bacchi, Cyrus [Journal of Medicinal Chemistry,2003,vol. 46,# 6,p. 1041 - 1048]