ChemicalBook >> CAS DataBase List >>4-Fluorobenzonitrile
4-Fluorobenzonitrile
- CAS No.
- 1194-02-1
- Chemical Name:
- 4-Fluorobenzonitrile
- Synonyms
- PFBN;P-FLUOROBENZONITRILE;For fluorobenzonitrile;4-fluoronitrile;4-florobenzonitrile;P-Fluorobenzonitile;4-fluoro-benzonitril;p-Cyanofluorobenzene;p-fluoro-benzonitril;4-CYANOFLUOROBENZENE
- CBNumber:
- CB5200760
- Molecular Formula:
- C7H4FN
- Molecular Weight:
- 121.11
- MDL Number:
- MFCD00001812
- MOL File:
- 1194-02-1.mol
- MSDS File:
- SDS
Last updated:2024-12-18 14:08:52
| Melting point | 32-34 °C (lit.) |
|---|---|
| Boiling point | 188 °C/750 mmHg (lit.) |
| Density | 1.1070 |
| refractive index | 1.4925 |
| Flash point | 150 °F |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | soluble in Chloroform, Ethyl Acetate |
| form | Crystalline Low Melting Solid |
| color | White |
| Water Solubility | Insoluble in water. |
| BRN | 2041517 |
| Exposure limits | NIOSH: IDLH 25 mg/m3 |
| InChIKey | AEKVBBNGWBBYLL-UHFFFAOYSA-N |
| CAS DataBase Reference | 1194-02-1(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | 4VJG35CQV3 |
| NIST Chemistry Reference | Benzonitrile, 4-fluoro-(1194-02-1) |
| EPA Substance Registry System | 4-Fluorobenzonitrile (1194-02-1) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS02,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H228-H302+H312+H332 | |||||||||
| Precautionary statements | P210-P240-P280-P301+P312-P302+P352+P312-P304+P340+P312 | |||||||||
| Hazard Codes | Xn,T,Xi | |||||||||
| Risk Statements | 20/21/22-36/37/38 | |||||||||
| Safety Statements | 36/37-36/37/39-26-36 | |||||||||
| RIDADR | UN 1325 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | DI4368500 | |||||||||
| Hazard Note | Toxic | |||||||||
| TSCA | T | |||||||||
| HazardClass | 4.1 | |||||||||
| PackingGroup | Ⅱ | |||||||||
| HS Code | 29269095 | |||||||||
| Toxicity | mouse,LD50,intraperitoneal,1gm/kg (1000mg/kg),Farmaco, Edizione Scientifica. Vol. 41, Pg. 41, 1986. | |||||||||
| NFPA 704 |
|
4-Fluorobenzonitrile price More Price(35)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 139416 | 4-Fluorobenzonitrile 99% | 1194-02-1 | 5g | $30.84 | 2024-03-01 | Buy |
| Sigma-Aldrich | 139416 | 4-Fluorobenzonitrile 99% | 1194-02-1 | 25g | $58.3 | 2024-03-01 | Buy |
| TCI Chemical | F0221 | 4-Fluorobenzonitrile >99.0%(GC) | 1194-02-1 | 25g | $28 | 2024-03-01 | Buy |
| TCI Chemical | F0221 | 4-Fluorobenzonitrile >99.0%(GC) | 1194-02-1 | 100g | $60 | 2024-03-01 | Buy |
| Alfa Aesar | A13028 | 4-Fluorobenzonitrile, 99% | 1194-02-1 | 5g | $24.65 | 2024-03-01 | Buy |
4-Fluorobenzonitrile Chemical Properties,Uses,Production
Chemical Properties
white crystalline low melting solid
Uses
4-Fluorobenzonitrile is used as chemical intermediate, solvent for perfumes and pharmaceuticals, stabilizer for chlorinated solvents, HPLC analysis, catalyst and component of transition-metal complex catalysts.
Uses
4-Fluorobenzonitrile is used in the synthesis of flurenones, pharmaceutical prerequisites, as well as opiod receptor antagonists.
Definition
ChEBI: 4-Fluorobenzonitrile is a member of benzenes and a nitrile.
General Description
4-Fluorobenzonitrile undergoes metal-mediated coupling to yield eight-membered thorium(IV) tetraazamacrocycle. It undergoes condensation with diphenylamine to yield monomer 4-cyanotriphenylamine.
Synthesis
4-Fluorobenzonitrile is synthesised using 4-Fluorobenzyl alcohol as raw material by chemical reaction. The specific synthesis steps are as follows:
With respect to 2 mmol of each alcohol represented by the general formula (1), 4 ml of CH2Cl2 as a solvent, 0.05 equivalent of TEMPO as an N-nitrosyl compound, (A) t-BuOCl, (B) I 2 or (C ) N, N'-diiodo-5,5-dimethylhydantoin (DIH) were mixed in a predetermined amount and stirred for a predetermined time at room temperature.Next, 1.5 equivalents of I 2 and 4 ml of aqueous ammonia were added, and the mixture was stirred at room temperature for 2 hours.
4-Fluorobenzonitrile Preparation Products And Raw materials
Raw materials
Preparation Products
4-MORPHOLINOBENZYLAMINE
4-Fluorobenzamidine hydrochloride
4-PIPERAZIN-1-YL-BENZOIC ACID
4-FLUORO-BENZAMIDINE
3-FLUORO-2-(5,5-DIMETHYL-1,3,2-DIOXABORINAN-2-YL)BENZONITRILE
4,4'-(piperazine-1,4-diyl)dibenzonitrile
2-Bromo-4-fluorobenzonitrile
4-N-BUTOXYBENZONITRILE
3,5-DiMethylMorpholine
Methyl 4-Mercaptobenzoate
1of4
Global( 596)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| EAST STAR BIOTECH (SUZHOU) CO., LTD. | +8617706846989 | marketing@eaststarbio.com | China | 48 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5889 | 58 |
| Hebei Jingbo New Material Technology Co., Ltd | +8619931165850 | hbjbtech@163.com | China | 1000 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20283 | 58 |
| Hebei Saisier Technology Co., LTD | +86-18400010335 +86-18034520335 | admin@hbsaisier.cn | China | 1016 | 58 |
| Hebei Longbang Technology Co., LTD | +86-18633929156 +86-18633929156 | admin@hblongbang.com | China | 941 | 58 |
| HebeiShuoshengImportandExportco.,Ltd | +86-18532138899 +86-18532138899 | L18532138899@163.com | China | 939 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29791 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 18751 | 58 |
| Hi-Tech Chemistry Corp | 0519-86626038 | yuhh@hitechem.com | CHINA | 810 | 58 |
View Lastest Price from 4-Fluorobenzonitrile manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-12-26 | 4-Fluorobenzonitrile
1194-02-1
|
US $6.00 / kg | 1kg | 99% | 2000KG/Month | HebeiShuoshengImportandExportco.,Ltd | |
 |
2024-12-24 | 4-Fluorobenzonitrile
1194-02-1
|
US $6.00 / kg | 1kg | More than 99% | 2000KG/Month | Hebei Longbang Technology Co., Ltd | |
 |
2024-11-07 | 4-Fluorobenzonitrile
1194-02-1
|
US $8.00 / kg | 1kg | 99% | 2000000 | Hebei Jingbo New Material Technology Co., Ltd |
-
- 4-Fluorobenzonitrile
1194-02-1
- US $6.00 / kg
- 99%
- HebeiShuoshengImportandExportco.,Ltd
-
- 4-Fluorobenzonitrile
1194-02-1
- US $6.00 / kg
- More than 99%
- Hebei Longbang Technology Co., Ltd
-
- 4-Fluorobenzonitrile
1194-02-1
- US $8.00 / kg
- 99%
- Hebei Jingbo New Material Technology Co., Ltd
1194-02-1(4-Fluorobenzonitrile)Related Search:
4-Fluoronitrobenzene
4-Fluorophenoxyacetic acid
Methyl 4-fluorobenzoate
Ethyl 4-fluorobenzoate
4-Fluorobenzoic acid
4-Fluorobenzyl chloride
4-Fluorophenylacetic acid
4-Bromofluorobenzene
4-Fluorothiophenol
4-Fluoromandelic acid
1of4
Benzonitrile, p-fluoro- (6CI,7CI,8CI)
The fluorine benzene nitriles
4-Fluorobenzonitrile, 97+%
p-Fluorophenyl cyanide
P-Fluorobenzonitile
p-Fluorobenzonitrile 4-Fluorobenzonitrile
4-florobenzonitrile
3-chloro-4-fluorobenzontrile
4-Fluorobenzonitrile98%
1-Cyano-4-fluorobenzene
1-Fluoro-4-cyanobenzene
4-fluoro-benzonitril
Benzonitrile, p-fluoro-
p-Cyanofluorobenzene
p-fluoro-benzonitril
4-CYANOFLUOROBENZENE
4-FLUOROBENZONITRILE
4-Fluorobenzonitrile>
Crisaborole Related Compound 1
Benzonitrile, 4-fluoro-
4-Fluorobenzonitrile pure, 98%
PFBN
P-FLUOROBENZONITRILE
For fluorobenzonitrile
Para Fluoro Benzonitrile
4-fluoronitrile
Olaquindox Impurity 13
1194-02-1
Organic Building Blocks
Nitrogen Compounds
Cyanides/Nitriles
Building Blocks for Liquid Crystals
Benzonitriles (Building Blocks for Liquid Crystals)
Building Blocks
C6 to C7
Pesticide intermediates
Pyridines
Fluorobenzene Series
Aromatic Nitriles
Fluorobenzene
Nitrile
Nitriles
Fluorine Compounds
Benzonitriles (Building Blocks for Liquid Crystals)
Building Blocks for Liquid Crystals
Functional Materials
C6 to C7
Cyanides/Nitriles
Nitrogen Compounds
bc0001
1194-02-1