ChemicalBook CAS DataBase List 4-(4-Methoxyphenyl)-2(3H)-thiazolone hydrazone

4-(4-Methoxyphenyl)-2(3H)-thiazolone hydrazone synthesis

8synthesis methods

Product Name:4-(4-Methoxyphenyl)-2(3H)-thiazolone hydrazone
CAS Number:4871-25-4
Molecular formula:C10H11N3OS
Molecular Weight:221.28

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4-(4-Methoxyphenyl)-2(3H)-thiazolone hydrazone

4871-25-4
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Yield:4871-25-4 Ca. 75.44 %

Reaction Conditions:

with potassium acetate in ethanol at 20;

Steps:

1.1

Thiosemicarbazide (0.91g, 10mmol) and p-methoxy-2-bromoacetophenone (2.28g, 10mmol) were slowly added to an aqueous ethanol solution containing potassium acetate (0.98g, 10mmol) (38mL, EtOH/H2O=1:1, V:V), stirred for 3h at room temperature, filtered after the reaction was completed, and then rinsed with 10mL of ice ethanol and vacuum dried to obtain white solid compound 4-(4- Methoxyphenyl)-2-hydrazinothiazole (1.67g), without further treatment, the yield was about 75.44%.

References:

CN115448915,2022,A Location in patent:Paragraph 0035-0038

2104-04-3 Synthesis