![](/CAS/GIF/13362-78-2.gif)
4,4'-Vinylenedipyridine synthesis
- Product Name:4,4'-Vinylenedipyridine
- CAS Number:13362-78-2
- Molecular formula:C12H10N2
- Molecular Weight:182.22
![4-Methylpyridine](/CAS/GIF/108-89-4.gif)
108-89-4
319 suppliers
$15.00/25mL
![4-Pyridinecarboxaldehyde](/CAS/GIF/872-85-5.gif)
872-85-5
483 suppliers
$10.00/1g
![4,4'-Vinylenedipyridine](/CAS/GIF/13362-78-2.gif)
13362-78-2
186 suppliers
$9.00/250mg
Yield:13362-78-2 49%
Reaction Conditions:
with acetic acid;lithium diisopropyl amide in tetrahydrofuran at -70; for 24 h;Darkness;Reflux;Knoevenagel Condensation;
Steps:
Ligand pypy
400μL (4.12mmol) of 4-picoline reacted with 3.0mL (4.32mmol) of LDA in THF (5mL) at -70°C. In the absence of light, 465mL (4.12mmol) of 4-piridincarboxyaldehyde was dropwise added with continuous stirring. After 24h of reflux in the presence of 10mL of acetic acid, the reaction mixture led to a yellow solution, from which a pale-yellow solid was separated by rotatory evaporation. The solid was purified employing column chromatography in analogous conditions to the ones previously mentioned (368mg, 49%). 1H RMN (400MHz, CDCl3, δ): 8.62 (d, J=4Hz, 4H, Ar-H), 7.61 (d, J=4Hz, 4H, Ar-H), 7.55 (s, 2H, -CH=CH-).
References:
Luzardo, Florencia;Álvarez, Natalia;Kremer, Carlos;de Camargo, Andrea S.S.;Gancheff, Jorge S. [Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy,2017,vol. 183,p. 45 - 52]
![4-Methylpyridine](/CAS/GIF/108-89-4.gif)
108-89-4
319 suppliers
$15.00/25mL
![4,4'-Vinylenedipyridine](/CAS/GIF/13362-78-2.gif)
13362-78-2
186 suppliers
$9.00/250mg
![1,2-BIS(4-PYRIDYL)ETHANE](/CAS/GIF/4916-57-8.gif)
4916-57-8
125 suppliers
$30.00/250mg
![4,4'-Vinylenedipyridine](/CAS/GIF/13362-78-2.gif)
13362-78-2
186 suppliers
$9.00/250mg
![Pyridine, 4,4',4'',4'''-(1,2,3,4-cyclobutanetetrayl)tetrakis-](/CAS/20210111/GIF/925681-86-3.gif)
925681-86-3
1 suppliers
inquiry
![4,4'-Vinylenedipyridine](/CAS/GIF/13362-78-2.gif)
13362-78-2
186 suppliers
$9.00/250mg