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4-(5-FORMYL-FURAN-2-YL)-2-HYDROXY-BENZOIC ACID synthesis

5synthesis methods
Benzoic acid, 4-(5-formyl-2-furanyl)-2-hydroxy-, methyl ester

1277116-14-9
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Yield:436088-45-8 95%

Reaction Conditions:

with sodium hydroxide in tetrahydrofuran;methanol; for 12 h;Reflux;Inert atmosphere;

References:

Tiberi, Marika;Tintori, Cristina;Ceresola, Elisa Rita;Fazi, Roberta;Zamperini, Claudio;Calandro, Pierpaolo;Franchi, Luigi;Selvaraj, Manikandan;Botta, Lorenzo;Sampaolo, Michela;Saita, Diego;Ferrarese, Roberto;Clementi, Massimo;Canducci, Filippo;Botta, Maurizio [Antimicrobial Agents and Chemotherapy,2014,vol. 58,# 6,p. 3043 - 3052] Location in patent:supporting information

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