4-Amino-2-ethoxypyridine synthesis
- Product Name:4-Amino-2-ethoxypyridine
- CAS Number:89943-12-4
- Molecular formula:C7H10N2O
- Molecular Weight:138.17
7598-35-8
363 suppliers
$6.00/250mg
89943-12-4
93 suppliers
$25.00/250mg
Yield: 76%
Reaction Conditions:
with sodium hydroxide in ethanol;water
Steps:
19.l f
l) 2-Ethoxy-4-aminopyridine (Den Hertog, Kolder and Combe, 1951) 2-Bromo-4-aminopyridine (4 g). solid sodium hydroxide (4 g) and ethanol (15 ml) were heated in a bomb at 160° C. for 6 hours and allowed to cool. Water was then added and the solvent partially removed under reduced pressure. The mixture was then extracted with ether and the solvent removed, leaving a clear oil of 2-Ethoxy-4-aminopyridine (164 g, 76%) which slowly crystallized into colourless needles, m.p. 88-89° C.
References:
Polychip Pharmaceuticals Pty Ltd;The University of Sydney US5929082, 1999, A
14432-12-3
537 suppliers
$5.00/5g
64-17-5
724 suppliers
$10.00/50g
89943-12-4
93 suppliers
$25.00/250mg
14432-12-3
537 suppliers
$5.00/5g
89943-12-4
93 suppliers
$25.00/250mg
26452-80-2
406 suppliers
$7.00/5g
89943-12-4
93 suppliers
$25.00/250mg
1124-33-0
330 suppliers
$10.00/1g
89943-12-4
93 suppliers
$25.00/250mg