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22669-27-8

4-AMINOBENZOIC ACID HCL synthesis

3synthesis methods
-

Yield:22669-27-8 85%

Reaction Conditions:

Stage #1: 4-nitro-benzoic acidwith sodium tetrahydroborate;water at 20; for 6 h;
Stage #2: with hydrogenchloride in ethyl acetate;chemoselective reaction;

References:

Yang, Fan;Chi, Cheng;Wang, Chunxia;Wang, Ying;Li, Yongfeng [Green Chemistry,2016,vol. 18,# 15,p. 4254 - 4262] Location in patent:supporting information

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