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ChemicalBook CAS DataBase List 4-AMINOISOINDOLIN-1-ONE

4-AMINOISOINDOLIN-1-ONE synthesis

7synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 3 steps
1: 98 percent / N-bromosuccinimide; 2,2'-azobisisobutyronitrile / CH2Cl2 / 16 h / Heating
2: 81 percent / ammonia / methanol / 2 h / 20 °C
3: 83 percent / ammonium formate / Pd/C / dimethylformamide / 0.5 h / 100 °C

References:

Jagtap, Prakash G.;Southan, Garry J.;Baloglu, Erkan;Ram, Siya;Mabley, Jon G.;Marton, Anita;Salzman, Andrew;Szabo, Csaba [Bioorganic and Medicinal Chemistry Letters,2004,vol. 14,# 1,p. 81 - 85]

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