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4-bromo-1-tosyl-1H-indole-3-carbaldehyde synthesis

5synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: 53 percent / POCl3 / 16 h / y
2: 64 percent / K2CO3 / 1,2-dimethoxy-ethane / 20 h / Ambient temperature

References:

Ralbovsky, Janet L.;Scola, Paul M.;Sugino, Eiichi;Burgos-Garcia, Carolina;Weinreb, Steven M.;Parvez, Masood [Heterocycles,1996,vol. 43,# 7,p. 1497 - 1512]