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ChemicalBook CAS DataBase List 4-Bromo-5-methyl-2-thiophenecarbaldehyde

4-Bromo-5-methyl-2-thiophenecarbaldehyde synthesis

2synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1.1: N-Bromosuccinimide; acetic acid
2.1: n-butyllithium / hexane; tetrahydrofuran / 0.33 h / -78 °C / Inert atmosphere
2.2: -78 - 0 °C / Inert atmosphere

References:

Fredrich, Sebastian;Bonasera, Aurelio;Valderrey, Virginia;Hecht, Stefan [Journal of the American Chemical Society,2018,vol. 140,# 20,p. 6432 - 6440]

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