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4-CHLORO-2-METHYLACETOPHENONE synthesis

7synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: 2.) n-BuLi / 1.) THF, -20 deg C, 45 min. 2.) -20 deg C, 4 h
2: 2) H2O, H(1+) / 1.) THF, -42 deg C

References:

Comins, Daniel L.;Brown, Jack D. [Tetrahedron Letters,1983,vol. 24,# 49,p. 5465 - 5468]

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