![](/CAS/GIF/108-41-8.gif)
3-Chlorotoluene synthesis
- Product Name:3-Chlorotoluene
- CAS Number:108-41-8
- Molecular formula:C7H7Cl
- Molecular Weight:126.58
![1-Bromo-4-chloro-2-methylbenzene](/CAS/GIF/14495-51-3.gif)
14495-51-3
248 suppliers
$10.00/5g
![3-Chlorotoluene](/CAS/GIF/108-41-8.gif)
108-41-8
257 suppliers
$19.00/10g
![Toluene](/CAS/GIF/108-88-3.gif)
108-88-3
7 suppliers
$21.80/5 mL
Yield:108-41-8 21 %Chromat. ,108-88-3 40 %Chromat.
Reaction Conditions:
with Pd-γ-Fe2O3;potassium tert-butylate in isopropyl alcohol at 70; for 12 h;Inert atmosphere;Sealed tube;
Steps:
Dehalogenation of 2-Bromo-1,3,5-trimethylbenzene; 1,3,5-Trimethylbenzene (6a); Typical Procedure for the Dehalogenation Reaction
General procedure: To a dry glass reaction tube purged with argon and equipped with a magnetic stir bar were added 2-bromo-1,3,5-trimethylbenzene (5a; 40 μL, 0.26 mmol), Pd-γ-Fe2O3 (25 mg, 5 mol% Pd), NaOt-Bu (31 mg, 0.33 mmol), and i-PrOH (1 mL) and the sealed tube was heated at 70 °C for 12 h. GC-MS yield of 6a: 100%, based on naphthalene as standard.
References:
Ajdačić, Vladimir;Nikolić, Andrea;Simić, Stefan;Manojlović, Dragan;Stojanović, Zoran;Nikodinovic-Runic, Jasmina;Opsenica, Igor M. [Synthesis,2018,vol. 50,# 1,art. no. SS-2017-T0452-OP,p. 119 - 126]
![Toluene](/CAS/GIF/108-88-3.gif)
108-88-3
7 suppliers
$21.80/5 mL
![3-Chlorotoluene](/CAS/GIF/108-41-8.gif)
108-41-8
257 suppliers
$19.00/10g
![4-Chlorotoluene](/CAS/GIF/106-43-4.gif)
106-43-4
331 suppliers
$14.00/5g
![2-Chlorotoluene](/CAS/GIF/95-49-8.gif)
95-49-8
327 suppliers
$10.00/5g
![2,5-DICHLOROTOLUENE](/CAS/GIF/19398-61-9.gif)
19398-61-9
115 suppliers
$10.00/5 g
![3-Chlorotoluene](/CAS/GIF/108-41-8.gif)
108-41-8
257 suppliers
$19.00/10g
![2-Chlorotoluene](/CAS/GIF/95-49-8.gif)
95-49-8
327 suppliers
$10.00/5g
![Toluene](/CAS/GIF/108-88-3.gif)
108-88-3
7 suppliers
$21.80/5 mL