4-CYANO-4-PHENYLPIPERIDINE HYDROCHLORIDE synthesis
- Product Name:4-CYANO-4-PHENYLPIPERIDINE HYDROCHLORIDE
- CAS Number:51304-58-6
- Molecular formula:C12H15ClN2
- Molecular Weight:222.72
140-29-4
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51304-58-6
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Yield:-
Steps:
Multi-step reaction with 2 steps
1: sodium hydride / dimethyl sulfoxide / 18 h / 18 - 50 °C
2: hydrogenchloride / acetonitrile / 0.58 h / 0 °C
References:
Kuduk, Scott D.;Chang, Ronald K.;Di Marco, Christina N.;Pitts, Daniel R.;Greshock, Thomas J.;Ma, Lei;Wittmann, Marion;Seager, Matthew A.;Koeplinger, Kenneth A.;Thompson, Charles D.;Hartman, George D.;Bilodeau, Mark T.;Ray, William J. [Journal of Medicinal Chemistry,2011,vol. 54,# 13,p. 4773 - 4780]
158144-79-7
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51304-58-6
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