Welcome to chemicalbook!
Chinese English Japanese Germany Korea
400-158-6606
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

ChemicalBook CAS DataBase List 4-(cyclohexyloxy)aniline
39905-48-1

4-(cyclohexyloxy)aniline synthesis

9synthesis methods
-

Yield:39905-48-1 700 mg

Reaction Conditions:

with palladium 10% on activated carbon;hydrogen in methanol; for 16 h;

Steps:

71.b (b) 4-(Cyclohexyloxy)aniline

A stirred solution of 1 -(cyclohexyloxy)-4-nitrobenzene (1 g) in MeOH (15 mL) was purged with nitrogen and 10% Pd/C (0.721 g) was added. The reaction mixture was stirred for 16 ht under a hydrogen atmosphere (balloon). The reaction mixture was filtered through Celite and the filtrate was concentrated under reduced pressure to afford the titled compound (700 mg). LCMS m/z 192.1 (M+H)+.

References:

WO2017/153952,2017,A1 Location in patent:Page/Page column 147