4-DIMETHYLAMINOBUTYRIC ACID HYDROCHLORIDE synthesis
- Product Name:4-DIMETHYLAMINOBUTYRIC ACID HYDROCHLORIDE
- CAS Number:69954-66-1
- Molecular formula:C6H14ClNO2
- Molecular Weight:167.63
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69954-66-1
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Yield:-
Reaction Conditions:
with formic acid for 16 h;Reflux;Inert atmosphere;
Steps:
4-(Dimethylamino)butanoic acid-HCl
γ-Aminobutyric acid (1.00 g, 9.69 mmol) was dissolved in 90% formic acid (2.52 mL) and 37% formaldehyde (1.94 mL) and refluxed for 16 hrs. The resulting solution was cooled, acidified with cone. HC1, and evaporated to dryness. The resulting solid was azeotroped with toluene several times to remove all traces of formic acid. The solid was then recrystallized from acetonitrile to yield 4- (dimethylamino)butanoic acid as the HC1 salt, mp 148-149 °C.
References:
UNIVERSITY OF CONNECTICUT;BALUNAS, Marcy J.;PAVLIK, Christopher M.;GERWICK, William H. WO2014/18913, 2014, A2 Location in patent:Page/Page column 48
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69954-66-1
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881 suppliers
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69954-66-1
114 suppliers
$44.50/5g
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56-12-2
887 suppliers
$5.00/100mg
69954-66-1
114 suppliers
$44.50/5g
872-50-4
942 suppliers
$10.00/100ML
69954-66-1
114 suppliers
$44.50/5g