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(4-Fluoro(phenylsulfonyl)anilino)acetic acid synthesis

2synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: 1) NaH / 1) DMF, room temperature, 30 min.; 2) room temperature, overnight
2: NaOH / ethanol; H2O / 2 h / Heating

References:

DeRuiter, Jack;Borne, Ronald F.;Mayfield, Charles A. [Journal of Medicinal Chemistry,1989,vol. 32,# 1,p. 145 - 151]