ChemicalBook CAS DataBase List 4-(HYDROXYMETHYL)CYCLOHEXANONE

4-(HYDROXYMETHYL)CYCLOHEXANONE synthesis

6synthesis methods

Product Name:4-(HYDROXYMETHYL)CYCLOHEXANONE
CAS Number:38580-68-6
Molecular formula:C7H12O2
Molecular Weight:128.17

10596-05-1
0 suppliers
inquiry

4-(Hydroxymethyl)cyclohexanol (cis- and trans- mixture)

33893-85-5
60 suppliers
$24.00/100mg

1653-30-1 Synthesis

1653-30-1
98 suppliers
$26.00/5g

38580-68-6
121 suppliers
$80.30/0.5g

Yield:38580-68-6 73%

Reaction Conditions:

with NaBrO₃;acetic acid in Ce

Steps:

5 EXAMPLE 5
EXAMPLE 5 To acetic acid in which Ce (IV)/PFCP (50 mg, 0.027 mmole) and 200 mg of NaBrO₃ were dispersed and dissolved, 1.0 mmole of 1,10-undecane diol and 1.0 mmole of 4-hydroxymethyl cyclohexanol were added, respectively. The reaction mixture was heated for three hours at 55° C. and the product was purified with a column chromatography to yield 154 mg (82% yield) of 10-undecane-1-ol and 93 mg (73% yield) of 4-hydroxymethyl cyclohexanone.

References:

E. I. Du Pont de Nemours and Company US4617153, 1986, A

FullText

17159-79-4 Synthesis