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4-iodobutyraldehyde synthesis

5synthesis methods
2919-23-5 Synthesis
Cyclobutanol

2919-23-5
182 suppliers
$9.00/1g

4-iodobutyraldehyde

77406-93-0
2 suppliers
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Yield:77406-93-0 92%

Reaction Conditions:

Stage #1: cyclobutanolwith [bis(pyridine)iodine]+ tetrafluoroborate in dichloromethane at 20; for 12 h;UV-irradiation;
Stage #2: with sulfuric acid in water;

References:

Barluenga, Jose;Gonzalez-Bobes, Francisco;Ananthoju, Sreenivasa R.;Garca-Martn, Miguel A.;Gonzalez, Jose M. [Angewandte Chemie - International Edition,2001,vol. 40,# 18,p. 3389 - 3392]