ChemicalBook CAS DataBase List 4-IODPHENYLACETIC ACID METHYL ESTER

4-IODPHENYLACETIC ACID METHYL ESTER synthesis

10synthesis methods

Product Name:4-IODPHENYLACETIC ACID METHYL ESTER
CAS Number:63349-52-0
Molecular formula:C9H9IO2
Molecular Weight:276.07

1798-06-7
175 suppliers
$6.00/1g

63349-52-0
39 suppliers
$26.00/250mg

Yield: 98%

Reaction Conditions:

with hydrogenchloride in methanol;water at 20; for 24 h;

Steps:

83
Preparation 83 methyl 4-Iodophenylacetate To a stirred solution of 4-iodophenylacetic acid (5.0 g, 19.1 mmol) in MeOH (200 ML) was added 4N hydrochloric acid in dioxane (10 ML).The reaction mixture was stirred for 24 h at room temperature and then the solvent was removed under reduced pressure to give the title compound (5.17 g, 98% yield), which was used without further purification.

References:

Mammen, Mathai;Dunham, Sarah;Hughes, Adam;Lee, Tae Weon;Husfeld, Cralg;Stangeland, Eric US2004/167167, 2004, A1 Location in patent:Page/Page column 50

67-56-1 Synthesis