ChemicalBook CAS DataBase List 4-ISOXAZOLEBORONIC ACID PINACOL ESTER

4-ISOXAZOLEBORONIC ACID PINACOL ESTER synthesis

1synthesis methods

Product Name:4-ISOXAZOLEBORONIC ACID PINACOL ESTER
CAS Number:928664-98-6
Molecular formula:C9H14BNO3
Molecular Weight:195.02

847490-69-1 Synthesis

847490-69-1
76 suppliers
$38.00/250mg

61676-62-8 Synthesis

2-Isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

61676-62-8
312 suppliers
$10.00/5g

928664-98-6
115 suppliers
$14.00/100mg

Yield:928664-98-6 90%

Reaction Conditions:

Stage #1:4-iodoisoxazole with TurboGrignard in tetrahydrofuran at -78; for 0.5 h;Inert atmosphere;
Stage #2:2-Isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane in tetrahydrofuran at 0; for 4.5 h;Inert atmosphere;

References:

Morita, Taiki;Fuse, Shinichiro;Nakamura, Hiroyuki [Angewandte Chemie - International Edition,2016,vol. 55,# 43,p. 13580 - 13584][Angew. Chem.,2016,vol. 128,p. 13778 - 13782,5] Location in patent:supporting information

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4-ISOXAZOLEBORONIC ACID PINACOL ESTER Related Search:

ISOXAZOLE-5-CARBOXYLIC ACID 3-Isoxazolecarboxylic acid 5-ISOXAZOLEMETHANOL 2-(2,5-DibroMophenyl)-4,4,5,5-tetraMethyl-1,3,2-dioxaborolane methyl 2-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate 2-[(3-chlorophenyl)Methyl]-4,4,5,5-tetraMethyl-1,3,2-dioxaborolane ISOXAZOLE-4-CARBOXYLIC ACID ETHYL ESTER 4-hydroxyisoxazole 4-Isoxazolecarboxylic acid