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(4-METHOXYPHENYL)(2-PHENYL-1H-INDOL-3-YL)METHANONE synthesis

8synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 3 steps
1.1: i-Pr2NH; CuI / Pd(PPh3)2Cl2 / dimethylformamide
1.2: 87 percent / dimethylformamide / 1.5 h / 0 - 20 °C
2.1: tetrahydrofuran / 1.5 h / 0 °C
3.1: 60 percent / K2CO3 / Pd(PPh3)4 / acetonitrile / 45 °C

References:

Cacchi, Sandro;Fabrizi, Giancarlo;Parisi, Luca M. [Synthesis,2004,# 11,p. 1889 - 1894]