ChemicalBook CAS DataBase List 4-(P-IODOPHENYL)BUTYRIC ACID

4-(P-IODOPHENYL)BUTYRIC ACID synthesis

5synthesis methods

Product Name:4-(P-IODOPHENYL)BUTYRIC ACID
CAS Number:27913-58-2
Molecular formula:C10H11IO2
Molecular Weight:290.1

589-87-7 Synthesis

589-87-7
531 suppliers
$10.00/1g

27913-58-2
65 suppliers
$21.00/250mg

Yield:-

Steps:

Multi-step reaction with 3 steps
1.1: n-butyllithium / tetrahydrofuran; hexane / 0.5 h / -78 °C / Inert atmosphere
1.2: -78 °C / Inert atmosphere
2.1: tetrahydrofuran / 1 h / 20 °C / Inert atmosphere
3.1: chloro[1,3-bis(2,6-di-i-propylphenyl)imidazol-2-ylidene]copper(I); lithium methanolate / tetrahydrofuran / 24 h / 70 °C / 760.05 Torr / Inert atmosphere
3.2: Inert atmosphere

References:

Ohishi, Takeshi;Zhang, Liang;Nishiura, Masayoshi;Hou, Zhaomin [Angewandte Chemie - International Edition,2011,vol. 50,# 35,p. 8114 - 8117]

1821-12-1 Synthesis