ChemicalBook CAS DataBase List 4-PIPERAZIN-1-YL-BENZOIC ACID

4-PIPERAZIN-1-YL-BENZOIC ACID synthesis

3synthesis methods

Product Name:4-PIPERAZIN-1-YL-BENZOIC ACID
CAS Number:85474-75-5
Molecular formula:C11H14N2O2
Molecular Weight:206.24

4-[4-(tert-Butoxycarbonyl)piperazino]benzoic acid

162046-66-4
136 suppliers
$6.00/250mg

85474-75-5
76 suppliers
$86.00/250mg

Yield:85474-75-5 61%

Reaction Conditions:

in hydrogenchloride;methanol;

Steps:

7.a (a)

(a) 4-piperazin-1-yl-benzoic acid A mixture of 4-(4-(tert-butoxycarbonyl)piperazin-1-yl)benzoic acid (28 g, 91 mmol) in hydrochloric acid in methanol (300 mL) was stirred at room temperature for 4 h. The resulting precipitate was collected by filtration and concentrated to dryness to provide the title compound (17 g, 61% yield) as a white solid.

References:

US2012/114600,2012,A1

451-46-7 Synthesis

451-46-7
289 suppliers
$5.00/5g

85474-75-5
76 suppliers
$86.00/250mg

References

234082-33-8 Synthesis

tert-Butyl 4-(4-(ethoxycarbonyl)phenyl)piperazine-1-carboxylate

234082-33-8
38 suppliers
$55.00/250mg

85474-75-5
76 suppliers
$86.00/250mg

References

4-PIPERAZIN-1-YL-BENZOIC ACID Related Search:

3-(4-Methylpiperazin-1-yl)benzoic acid 4-Piperazin-1-yl-benzoic acid tert-butyl ester