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4-Piperidinemethanol, α-phenyl-, (αS)- synthesis

2synthesis methods
37586-22-4 Synthesis
4-BENZOYLPIPERIDINE HYDROCHLORIDE

37586-22-4
64 suppliers
$541.82/5g

4-Piperidinemethanol, α-phenyl-, (αS)-

957202-21-0
1 suppliers
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Yield:957202-21-0 77%

Reaction Conditions:

with bis(1,5-cyclooctadiene)diiridium(I) dichloride;potassium tert-butylate;hydrogen;isopropyl alcohol;(1R,2R)-N-(2-diphenylphosphanylbenzyl)cyclohexane-1,2-diamine in tert-butyl alcohol at 22; under 37503.8 Torr; for 42 h;Catalytic behavior;Autoclave;Schlenk technique;enantioselective reaction;Temperature;Time;

References:

Fuentes, Jose A.;Carpenter, Ian;Kann, Nina;Clarke, Matthew L. [Chemical Communications,2013,vol. 49,# 87,p. 10245 - 10247] Location in patent:supporting information