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ChemicalBook CAS DataBase List 4'-TRIFLUOROMETHYL-BIPHENYL-3-YLAMINE
400747-98-0

4'-TRIFLUOROMETHYL-BIPHENYL-3-YLAMINE synthesis

4synthesis methods
-

Yield:400747-98-0 83%

Reaction Conditions:

with potassium carbonate;tetrakis(triphenylphosphine) palladium(0) in N,N-dimethyl-formamide at 100; for 17 h;Suzuki coupling;

References:

Parrish, Cynthia A.;Adams, Nicholas D.;Auger, Kurt R.;Burgess, Joelle L.;Carson, Jeffrey D.;Chaudhari, Amita M.;Copeland, Robert A.;Diamond, Melody A.;Donatelli, Carla A.;Duffy, Kevin J.;Faucette, Leo F.;Finer, Jeffrey T.;Huffman, William F.;Hugger, Erin D.;Jackson, Jeffrey R.;Knight, Steven D.;Luo, Lusong;Moore, Michael L.;Newlander, Ken A.;Ridgers, Lance H.;Sakowicz, Roman;Shaw, Antony N.;Sung, Chiu-Mei M.;Sutton, David;Wood, Kenneth W.;Zhang, Shu-Yun;Zimmerman, Michael N.;Dhanak, Dashyant [Journal of Medicinal Chemistry,2007,vol. 50,# 20,p. 4939 - 4952]

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