ChemicalBook CAS DataBase List 5-Iodo-1H-pyrrole-2-carbaxaldehyde

5-Iodo-1H-pyrrole-2-carbaxaldehyde synthesis

2synthesis methods

Product Name:5-Iodo-1H-pyrrole-2-carbaxaldehyde
CAS Number:40566-13-0
Molecular formula:C5H4INO
Molecular Weight:221

5H,10H-Dipyrrolo[1,2-a:1',2'-d]pyrazine-5,10-diamine, N5,N5,N10,N10-tetramethyl-

64435-30-9
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40566-13-0
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Yield:40566-13-0 65%

Reaction Conditions:

Stage #1: N⁵,N⁵,N¹⁰,N¹⁰-tetramethyl-5,10-dihydrodipyrrolo[1,2-a:1',2'-d]pyrazine-5,10-diaminewith n-butyllithium in tetrahydrofuran;pentane at -15 - 20; for 1.75 h;
Stage #2: with iodine in tetrahydrofuran;pentane at -75 - 20;
Stage #3: with water;sodium acetate for 5 h;Reflux;

References:

Bowie, Alfred L.;Trauner, Dirk [Journal of Organic Chemistry,2009,vol. 74,# 4,p. 1581 - 1586] Location in patent:experimental part

1003-29-8
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$10.00/1g

40566-13-0
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1H-Pyrrole-2-carboxaldehyde, 4,5-diiodo-

35302-88-6
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References

5-Iodo-1H-pyrrole-2-carbaxaldehyde Related Search:

5-IODO-PYRIDINE-3-CARBALDEHYDE 5-Iodopyridine-2-carboxylic acid