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5-Methoxy-2-nitrobenzofuran synthesis

6synthesis methods
-

Yield:30335-72-9 83%

Reaction Conditions:

Stage #1: 2-Hydroxy-4-methoxybenzaldehyde;bromonitromethanewith potassium carbonate in acetone at 20; for 6 h;
Stage #2: with acetic anhydride in acetone; for 6 h;Reflux;

References:

Cheng, Bao;Lin, Yongsheng;Kuang, Ming;Fang, Sai;Gu, Qiong;Xu, Jun;Wang, Laiyou [Chemical Biology and Drug Design,2015,vol. 86,# 5,p. 1121 - 1130]