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ChemicalBook CAS DataBase List 5-PYRROLIDIN-1-YLPYRIDIN-2-AMINE

5-PYRROLIDIN-1-YLPYRIDIN-2-AMINE synthesis

2synthesis methods
39856-50-3 Synthesis
5-Bromo-2-nitropyridine

39856-50-3
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Yield:937623-38-6 321 mg

Reaction Conditions:

with palladium 10% on activated carbon;hydrogen at 35; under 760.051 Torr;

Steps:

25.2 Step 25.2: 5-Pyrrolidin-1 -ylpyridin-2-ylamine

Step 25.2: 5-Pyrrolidin-1 -ylpyridin-2-ylamine 410 mg (2.12 mmol) of the product obtained in step 25.1 are hydrogenated in the presence of 10% Pd/C at atmospheric pressure at 35°C. The solution obtained is evaporated under reduced pressure to give 321 mg of 5-pyrrolidin-1-ylpyridin-2-ylamine.

References:

WO2013/111106,2013,A1 Location in patent:Page/Page column 113

1448988-13-3 Synthesis
2-nitro-5-(pyrrolidin-1-yl)pyridine

1448988-13-3
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