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5-Quinolinecarboxylicacid,2-methyl-(8CI,9CI) synthesis

3synthesis methods
-

Yield:634-39-9 26%

Reaction Conditions:

with hydrogenchloride for 2 h;Heating;Doebner-Miller reaction;

References:

Polanski, Jaroslaw;Zouhiri, Fatima;Jeanson, Laurence;Desma?le, Didier;D'Angelo, Jean;Mouscadet, Jean-Fran?ois;Gieleciak, Rafal;Gasteiger, Johann;Le Bret, Marc [Journal of Medicinal Chemistry,2002,vol. 45,# 21,p. 4647 - 4654]