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ChemicalBook CAS DataBase List 4-AMINO-5-METHOXY-1,2-DIMETHYL-1H-INDOLE-3-CARBOXYLIC ACID ETHYL ESTER

4-AMINO-5-METHOXY-1,2-DIMETHYL-1H-INDOLE-3-CARBOXYLIC ACID ETHYL ESTER synthesis

5synthesis methods
52535-61-2 Synthesis
Ethyl 5-methoxy-1,2-dimethyl-4-nitroindole-3-carboxylate

52535-61-2
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Yield:52535-65-6 80%

Reaction Conditions:

with hydrogenchloride;tin in ethanol; for 0.5 h;Heating;

References:

Naylor, Matthew A.;Swann, Elizabeth;Everett, Steven A.;Jaffar, Mohammed;Nolan, John;Robertson, Naomi;Lockyer, Stacey D.;Patel, Kantilal B.;Dennis, Madeleine F.;Stratford, Michael R. L.;Wardman, Peter;Adams, Gerald E.;Moody, Christopher J.;Stratford, Ian J. [Journal of Medicinal Chemistry,1998,vol. 41,# 15,p. 2720 - 2731]