ChemicalBook CAS DataBase List (E)-2-Methyl-4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)but-3-en-2-ol

(E)-2-Methyl-4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)but-3-en-2-ol synthesis

5synthesis methods

Product Name:(E)-2-Methyl-4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)but-3-en-2-ol
CAS Number:581802-26-8
Molecular formula:C11H21BO3
Molecular Weight:212.09

115-19-5 Synthesis

115-19-5
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73183-34-3
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(E)-2-Methyl-4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)but-3-en-2-ol

581802-26-8
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$45.00/10mg

Yield:581802-26-8 97%

Reaction Conditions:

with sodium methylate;Cu⁽²⁺⁾*4Cu⁽¹⁺⁾*4I^(1-)*2C₅H₃N₂O₂^(1-)*C₅H₅N*C₂H₇N*3C₃H₇NO in ethanol at 25; for 1 h;Inert atmosphere;

Steps:

2.3. Typical procedure for the hydroborylation of alkynes

General procedure: The typical experimental procedure for the hydroborylation ofalkynes is as follows: a mixture of alkyne (2 mmol), compound 1(0.006 mmol), bis(pinacolato)diboron (2.5 mmol), NaOMe(0.2 mmol) and 5 mL EtOH were successively added into a reaction flask equipped with a Ar (99.99%) balloon. Then the flask was vacuumedand charged in Ar three times to exclude air in the reactionsystem. Subsequently, the obtained reaction mixture was magneticallystirred at 25 °C for 1 h. After the reaction was completed, thecatalysts were separated by filtration and the yield was determinedby GC analysis. The pure products were obtained by columnchromatography on silica gel (petroleum ether/ethyl acetate as aneluent).

References:

Gao, Ning;Hu, Tianding;Kang, Xiaomin;Lan, Xingwang;Wang, Zhenguang;Wu, Zhi-Lei;Zhao, Bin [Journal of Catalysis,2021,vol. 404,p. 250 - 257]

115-19-5 Synthesis

115-19-5
263 suppliers
$20.00/25mL