(R)-3-METHYL-1-[3-(TRIFLUOROMETHYL)PYRIDIN-2-YL]PIPERAZINE synthesis
1synthesis methods
- Product Name:(R)-3-METHYL-1-[3-(TRIFLUOROMETHYL)PYRIDIN-2-YL]PIPERAZINE
- CAS Number:582325-05-1
- Molecular formula:C11H14F3N3
- Molecular Weight:245.24
Yield:582325-05-1 86%
Reaction Conditions:
with copper;potassium carbonate in N,N-dimethyl-formamide at 130;
References:
Ognyanov, Vassil I.;Balan, Chenera;Bannon, Anthony W.;Bo, Yunxin;Dominguez, Celia;Fotsch, Christopher;Gore, Vijay K.;Klionsky, Lana;Ma, Vu V.;Qian, Yi-Xin;Tamir, Rami;Wang, Xianghong;Xi, Ning;Xu, Shimin;Zhu, Dawn;Gavva, Narender R.;Treanor, James J. S.;Norman, Mark H. [Journal of Medicinal Chemistry,2006,vol. 49,# 12,p. 3719 - 3742]