Welcome to chemicalbook!
Chinese English Japanese Germany Korea
400-158-6606
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

2-BroMo-4-trifluoroMethyl-3-quinolinecarboxylic acid synthesis

2synthesis methods
-

Yield:590372-20-6 81%

Reaction Conditions:

Stage #1: 2-bromo-4-(trifluoromethyl)quinolinewith n-butyllithium;diisopropylamine in tetrahydrofuran;hexane at -75; for 2 h;
Stage #2: carbon dioxideFurther stages.;

References:

Lefebvre, Olivier;Marull, Marc;Schlosser, Manfred [European Journal of Organic Chemistry,2003,# 11,p. 2115 - 2121]