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(1R,3R)-1,2,2-Trimethylcyclopentane-1,3-dicarboxylic acid synthesis

7synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: water
2: glacial acetic acid; concentrated hydrochloric acid / 170 - 180 °C / Behandlung des Reaktionsproduktes mit Acetylchlorid

References:

Aschan;Havulinna [Chemisches Zentralblatt,1918,vol. 89,# II,p. 954]