6,7-dichloroquinoline-5,8-dione synthesis

5synthesis methods

Product Name:6,7-dichloroquinoline-5,8-dione
CAS Number:6541-19-1
Molecular formula:C9H3Cl2NO2
Molecular Weight:228.03

21302-43-2 Synthesis

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6541-19-1
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Yield:6541-19-1 90%

Reaction Conditions:

with hydrogenchloride;sodium chlorate at 50 - 60; for 0.5 h;

Steps:

3 EXAMPLE 3, 6,7-dichloro-5,8-quinolindion of Formula 2
EXAMPLE 3 6,7-dichloro-5,8-quinolindion of Formula 2 After addition of 5-amino-8-hydroxyquinoline dihydrochloride (9 g) to hydrochloric acid (81 g), the reaction mixture was heated to 60° C. and NaClO₃ (4.5 g) was added. The reaction mixture was stirred for 30 min at 50-60° C., filtered and recrystallized twice with buthanol to give yellow precipitate of 6,7-dichloro-5,8-quinolindion (90%).

References:

Il Jin Copper Foil Corp. US6818653, 2004, B1 Location in patent:Page column 5

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148-24-3 Synthesis