6-BROMO-5-METHYL[1,2,4]TRIAZOLO[1,5-A]PYRIDINE synthesis

Yield:-

Steps:

Multi-step reaction with 2 steps
1: DMF / 12 h / 130 °C
2: pyridine; hydroxylamine-O-sulfonic acid / methanol / 20 °C

References:

Edmondson, Scott D.;Mastracchio, Anthony;Mathvink, Robert J.;He, Jiafang;Harper, Bart;Park, You-Jung;Beconi, Maria;Di Salvo, Jerry;Eiermann, George J.;He, Huaibing;Leiting, Barbara;Leone, Joseph F.;Levorse, Dorothy A.;Lyons, Kathryn;Patel, Reshma A.;Patel, Sangita B.;Petrov, Aleksandr;Scapin, Giovanna;Shang, Jackie;Roy, Ranabir Sinha;Smith, Aaron;Wu, Joseph K.;Xu, Shiyao;Zhu, Bing;Thornberry, Nancy A.;Weber, Ann E. [Journal of Medicinal Chemistry,2006,vol. 49,# 12,p. 3614 - 3627]