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ChemicalBook CAS DataBase List 6-CHLORO-4-CHLOROMETHYL-7-HYDROXY-CHROMEN-2-ONE

6-CHLORO-4-CHLOROMETHYL-7-HYDROXY-CHROMEN-2-ONE synthesis

2synthesis methods
-

Yield:223420-30-2 99%

Steps:

1 6-Chloro-4-chloromethyl-7-hydroxycoumarin (12).

6-Chloro-4-chloromethyl-7-hydroxycoumarin (12). This compound was prepared by the same method as compound 11, starting with 4-chlororesorcinol rather than 4-bromoresorcinol, to yield 2.50 g (99% yield) of compound 12 as a solid. 1H NMR (CD3OD) δ 7.96 (1H, s), 6.86 (1H, s), 6.43 (1H, s), 4.83 (2H, s).

References:

US2002/16472,2002,A1

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