ChemicalBook CAS DataBase List 6-METHYLAMINO-1,3-DIMETHYLURACIL

6-METHYLAMINO-1,3-DIMETHYLURACIL synthesis

12synthesis methods

Product Name:6-METHYLAMINO-1,3-DIMETHYLURACIL
CAS Number:5770-42-3
Molecular formula:C7H11N3O2
Molecular Weight:169.18

6972-27-6 Synthesis

6-Chloro-1,3-dimethyl-2,4-(1H,3H)-pyrimidinedione

6972-27-6
222 suppliers
$6.00/1g

74-89-5 Synthesis

74-89-5
7 suppliers
$13.44/25ML

5770-42-3
25 suppliers
inquiry

Yield:5770-42-3 95%

Reaction Conditions:

in methanol; for 16 h;Large scale;

Steps:

2 (2) Preparation of 1,3-dimethyl-6-methylaminopyrimidine-2,4-dione (Preparation of compound SM3)

The compound SM2 (6.5 kg, 37.3mol) was dissolved in 50L methanol. Drop methylamine alcohol solution 50L, reaction 16 hours, HPLC monitoring, after the reaction, concentrated, and adding water (20L), the ethyl acetate extract (20L * 3), combined with the organic phase, saturated salt water washing (10L), anhydrous sodium sulfate drying, filtering, reduced pressure distillation to remove the organic phase, dried under vacuum to get white solid 6.0 kg, is fine compound SM3, yield: 95.0%.

References:

CN103755705,2017,B Location in patent:Paragraph 0033; 0037; 0038

6972-27-6 Synthesis

6972-27-6
222 suppliers
$6.00/1g