ChemicalBook CAS DataBase List 6-NITRO-1H-PYRROLO[2,3-B]PYRIDINE

6-NITRO-1H-PYRROLO[2,3-B]PYRIDINE synthesis

6synthesis methods

Product Name:6-NITRO-1H-PYRROLO[2,3-B]PYRIDINE
CAS Number:145901-11-7
Molecular formula:C7H7N3
Molecular Weight:133.15

55052-27-2 Synthesis

55052-27-2
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$23.00/1g

145901-11-7
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$45.00/100mg

Yield: 72%

Reaction Conditions:

with ammonium hydroxide at 20 - 120; for 5 h;

Steps:

1C step C: 6-amino-7-azaindole
At room temperature, concentrated aqueous ammonia (40 mL) was added drop-wise to 6-chloro-7-azaindole (3.20 g, 0.024mol), after the tube is heated, the reaction is heated at 120 ° C for 5h. The reaction is complete, cooling, filter and then obtained a brown solid product (2.00 g, 72%).

References:

Ding Min CN108997343, 2018, A Location in patent:Paragraph 0017; 0018; 0026-0029