6-(trifluoromethyl)-5H-purin-2-amine synthesis
- Product Name:6-(trifluoromethyl)-5H-purin-2-amine
- CAS Number:2993-20-6
- Molecular formula:C6H4F3N5
- Molecular Weight:203.12
19690-23-4
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Yield:-
Steps:
Multi-step reaction with 3 steps
1: 63 percent / HCl, H2O / dimethylformamide / 6 h / 60 °C
2: 27 percent / KF, CuI, NMP / dimethylformamide / 24 h / 60 °C
3: 92 percent / Dowex 50 X 8 (H(+)), H2O / methanol / 1 h / Heating
References:
Hocek, Michal;Holy, Antonin [Collection of Czechoslovak Chemical Communications,1999,vol. 64,# 2,p. 229 - 241]
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2993-20-6
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