8-ethyl-5-oxo-2-[4-[[3-(trifluoromethyl)phenyl]carbamothioyl]piperazin-1-yl]pyrido[2,3-d]pyrimidine-6-carboxylic acid synthesis
- Product Name:8-ethyl-5-oxo-2-[4-[[3-(trifluoromethyl)phenyl]carbamothioyl]piperazin-1-yl]pyrido[2,3-d]pyrimidine-6-carboxylic acid
- CAS Number:634175-34-1
- Molecular formula:C22H21F3N6O3S
- Molecular Weight:506.5
51940-44-4
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634175-34-1
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Yield:634175-34-1 75%
Reaction Conditions:
with triethylamine in N,N-dimethyl-formamide at 20;Inert atmosphere;
References:
Hoeglund, Adrienne B.;Bostic, Heidi E.;Howard, Angela L.;Wanjala, Irene W.;Best, Michael D.;Baker, Daniel L.;Parrill, Abby L. [Journal of Medicinal Chemistry,2010,vol. 53,# 3,p. 1056 - 1066] Location in patent:experimental part