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4-(2-HYDROXYETHYL)-5-METHYL-1,2-DIHYDRO-3H-PYRAZOL-3-ONE synthesis

1synthesis methods
-

Yield:65287-96-9 65%

Reaction Conditions:

with hydrazine hydrate in water; for 2 h;Heating;Ring cleavage;cyclocondensation;

References:

Zimmermann, Diane;Janin, Yves Louis;Brehm, Lotte;Braeuner-Osborne, Hans;Ebert, Bjarke;Johansen, Tommy Norskov;Madsen, Ulf;Krogsgaard-Larsen, Povl [European Journal of Medicinal Chemistry,1999,vol. 34,# 11,p. 967 - 976]