(2S,4S)-1-(TERT-BUTOXYCARBONYL)-4-(3-CHLORO-PHENOXY)-2-PYRROLIDINECARBOXYLIC ACID synthesis

5synthesis methods

Product Name:(2S,4S)-1-(TERT-BUTOXYCARBONYL)-4-(3-CHLORO-PHENOXY)-2-PYRROLIDINECARBOXYLIC ACID
CAS Number:686766-56-3
Molecular formula:C16H20ClNO5
Molecular Weight:341.79

1,2-Pyrrolidinedicarboxylic acid, 4-(3-chlorophenoxy)-, 1-(1,1-dimethylethyl) 2-methyl ester, (2S,4S)-

686766-55-2
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(2S,4S)-1-(TERT-BUTOXYCARBONYL)-4-(3-CHLORO-PHENOXY)-2-PYRROLIDINECARBOXYLIC ACID

686766-56-3
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$322.00/500mg

Yield:686766-56-3 78%

Reaction Conditions:

with water;lithium hydroxide in tetrahydrofuran;

References:

Rawson, David J.;Brugier, Delphine;Harrison, Anthony;Hough, Jo;Newman, Julie;Otterburn, Joe;Maw, Graham N.;Price, Jenny;Thompson, Lisa R.;Turnpenny, Paul;Warren, Andrew N. [Bioorganic and Medicinal Chemistry Letters,2011,vol. 21,# 12,p. 3767 - 3770] Location in patent:scheme or table

24424-99-5 Synthesis