1-[(2R,3S,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione synthesis

10synthesis methods

Product Name:1-[(2R,3S,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
CAS Number:69256-17-3
Molecular formula:C10H13FN2O5
Molecular Weight:260.22

97614-43-2 Synthesis

Yield:-

Steps:

Multi-step reaction with 2 steps
1.1: 90 percent / HBr / CH₂Cl₂ / 24 h / 20 °C
2.1: CCl₄ / 72 h / 77 °C
2.2: NH₄OH / methanol / 24 h / 20 °C

References:

Elzagheid, Mohamed I;Tedeschi, Anna Lisa;Damha, Masad J [Nucleosides, nucleotides and nucleic acids,2003,vol. 22,# 5-8,p. 1343 - 1346]

97614-47-6 Synthesis

65-71-4 Synthesis

554-01-8 Synthesis

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