7-bromo-2-methoxyquinoxaline synthesis

5synthesis methods

Product Name:7-bromo-2-methoxyquinoxaline
CAS Number:212327-10-1
Molecular formula:C9H7BrN2O
Molecular Weight:239.07

67-56-1 Synthesis

67-56-1
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$9.00/25ml

89891-65-6
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$7.00/100mg

212327-10-1
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$61.00/100mg

Yield:212327-10-1 100%

Reaction Conditions:

with potassium carbonate for 2 h;Reflux;

Steps:

90

[0305] To a solution of 7-bromo-2-chloroquinoxaline (10 g, 41 mmol, 1 eq.) in CH₃OH ( 200 mL) was added K₂C0₃ ( 12.4 g, 91 mmol, 2 eq). The resulting mixture was stirred under reflux for 2h, then cooled to rt and concentrated. The resulting residue was dissolved in THF and filtered. The filtrate was concentrated to afford 7-bromo-2-methoxyquinoxaline as a white solid (9.88 g, 100%).

References:

WO2013/40515,2013,A1 Location in patent:Paragraph 0305