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700362-32-9

Benzenemethanol, 2-nitro-alpha-(trifluoromethyl)- (9CI) synthesis

2synthesis methods
-

Yield:700362-32-9 99%

Reaction Conditions:

Stage #1: (trifluoromethyl)trimethylsilane;2-nitro-benzaldehydewith potassium carbonate in N,N-dimethyl-formamide at 20; for 4 h;
Stage #2: with water in N,N-dimethyl-formamide; for 4 h;Acidic conditions;

References:

Cheng, Huicheng;Pei, Yu;Leng, Faqiang;Li, Jingya;Liang, Apeng;Zou, Dapeng;Wu, Yangjie;Wu, Yusheng [Tetrahedron Letters,2013,vol. 54,# 33,p. 4483 - 4486]