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8-Benzyloxy-2'-deoxy-D-guanosine synthesis

4synthesis methods
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Yield:96964-90-8 80%

Reaction Conditions:

Stage #1: benzyl alcoholwith sodium at 20; for 3 h;Metallation;
Stage #2: 8-bromo-2'-deoxyguanosine in dimethyl sulfoxide at 65; for 16 h;Substitution;

References:

Nampalli, Satyam;Kumar, Shiv [Bioorganic and Medicinal Chemistry Letters,2000,vol. 10,# 15,p. 1677 - 1679]

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