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3-(4-Chloro-6-methyl-7H-pyrrolo[2,3-d]pyrimidin-7-yl)propane-1,2-diol synthesis

1synthesis methods
13552-31-3 Synthesis
3-amino-1,2-propanediol, (±)

13552-31-3
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1-(4,6-dichloropyrimidin-5-yl)propan-2-one

26035-69-8
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3-(4-Chloro-6-methyl-7H-pyrrolo[2,3-d]pyrimidin-7-yl)propane-1,2-diol

80765-76-0
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Yield:80765-76-0 91%

Reaction Conditions:

in water at 100; for 4 h;

References:

Bisagni, Emile;Legraverend, Michel;Lhoste, Jean-Marc [Journal of Organic Chemistry,1982,vol. 47,# 8,p. 1500 - 1503]