ChemicalBook CAS DataBase List Ethyl 4-[[1-[(4-fluorophenyl)methyl]-1H-benzimidazol-2-yl]amino]piperidine-1-carboxylate

Ethyl 4-[[1-[(4-fluorophenyl)methyl]-1H-benzimidazol-2-yl]amino]piperidine-1-carboxylate synthesis

12synthesis methods

Product Name:Ethyl 4-[[1-[(4-fluorophenyl)methyl]-1H-benzimidazol-2-yl]amino]piperidine-1-carboxylate
CAS Number:84501-68-8
Molecular formula:C22H25FN4O2
Molecular Weight:396.46

58859-46-4 Synthesis

58859-46-4
218 suppliers
$13.00/5g

84946-20-3 Synthesis

1-(4-Fluorobenzyl)-2-chlorobenzimidazole

84946-20-3
231 suppliers
$8.00/1g

Ethyl 4-[[1-[(4-fluorophenyl)methyl]-1H-benzimidazol-2-yl]amino]piperidine-1-carboxylate

84501-68-8
23 suppliers
$821.00/25mg

Yield:84501-68-8 98%

Reaction Conditions:

in neat (no solvent) at 170; for 4 h;

References:

Kumar, Malkeet;Okombo, John;Mambwe, Dickson;Taylor, Dale;Lawrence, Nina;Reader, Janette;Van Der Watt, Mari?tte;Fontinha, Diana;Sanches-Vaz, Margarida;Bezuidenhout, Belinda C.;Lauterbach, Sonja B.;Liebenberg, Dale;Birkholtz, Lyn-Marie;Coetzer, Theresa L.;Prudêncio, Miguel;Egan, Timothy J.;Wittlin, Sergio;Chibale, Kelly [ACS Infectious Diseases,2019,vol. 5,# 2,p. 303 - 315]