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3-(4-METHOXY-PHENYL)-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER synthesis

6synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: dichloromethane / 20 °C / Molecular sieve; Inert atmosphere
2: 2,6-dimethylpyridine; copper(II) bis(trifluoromethanesulfonate) / dichloromethane / 12 h / 20 °C / Inert atmosphere

References:

Luescher, Michael U.;Vo, Cam-Van T.;Bode, Jeffrey W. [Organic Letters,2014,vol. 16,# 4,p. 1236 - 1239]